Antimicrobial Activity of Curcuma longa

MIC of aqueous extract of Curcuma longa
Staphylococcus Aureus 37.5% ( 375mg/ml)
Enterococcus Faecalis 37.5% ( 375mg/ml)
Candida Albicans 19% ( 190 mg/ml)


Anti microbial activity of turmeric natural dye against different bacterial strains.

Tested bacterial strains Turmeric powdered
25µl 50µl 100µl
Erythromycin 5mcg/disc
Salmonella paratyphi - - - -
Pseudomonas aeruginosa 10 11 13 17
Vibrio harveyi 7 9 12 7
E. coli 7 9 15 10
Entrococcus faecolis 10 11 14 -
Plesiomonas shigelloides - - - 9
Staphylococcus lutea 9 10 13 -
Vibrio alginolyticus 11 11 14 8
Vibrio mimicus - - - 9
Vibrio cholera 10 12 15 -


The in vitro, test confirmed the antimicrobial activity of turmeric extract against ten different bacterial strains. The antibacterial activity was measured by agar well diffusion method. Curcumin longa showed good inhibitory activity against E.coliand Vibrio cholera with a zone of inhibition 7mm to 15mm and 10mm to 15mm respectively.

Ref: Mari SelvamR et al. Anti-microbial Activity of Turmeric Natural Dyeagainst Different Bacterial Strains. Journal of Applied Pharmaceutical Science 02 (06); 2012: 210-212


♦ Inhibition zone (mm) of curcumin extract against Strept. mutans compared with Ciprofloxacin.
1=negative control,
2=curcumin,
3=Ciprofloxacin.

♦ Inhibition zone (mm) of curcumin extract against Strept. pyogenes compared with Ciprofloxacin.
1=negative control,
2=curcumin,
3=Ciprofloxacin.

Inhibition zone (mm) of methanolic extract of Curcumin against Sreptmutans & Streptpyogenes compared with Ciprofloxacin.


Agent or Inhibitor Strept. mutans Strepto. Pyogenes
Curcumin 9.7 ± 2.7* 10.2 ± 2.1
Ciprofloxacin 15.52 ± 3.10 13.4 ± 3

The mean of inhibition zone mm ± SD,* significant at 0.055

Ref : Mohammed N.A &Habi NY. Evaluation of Antimicrobial activity of curcumin against two oral bacteria Automation,Controland intelligent Systems2015; 3(2-1):18-21. Published online January 27, 2015
(http:www.sciencepublishinggroup.com/j/acis)doi:10.11648/j.acis.s.2015030201.14 ISSN:2328-5583 (Print), ISSN:2328-5591(Online)